The Royals settled for a draw in the matchday one fixture at the Accra Sports Stadium
Signed on local Transfer Deadline Day in September, the Ghana legend was declared not match-fit ahead of the matchweek one tie, having only returned to the pitch after a long absence.
In the end, two first-half goals saw Legon and Chelsea share the spoils at the Accra Sports Stadium.
Captain Stephen Amankona scored the opener for visiting Chelsea in the 22nd minute, converting from the spot after Kofi Owusu was fouled in the box.
In the 34th minute, Legon skipper Jonah Attuquaye restored parity for the hosts, also finding the back of the net from a penalty.
“Asamoah Gyan is one experienced player and he’s still got some problems with injury,” Legon Cities head coach Goran Barjaktarevic said ahead of Saturday’s season opener.
We are working to get him fit because it is very important when he comes back, he comes back in good shape.”
While Gyan was not on the pitch on Saturday, he still played a key role for The Royals from the sidelines.
It is unclear if he will play any part in the club’s next game, an away tie against Great Olympics in what will be a local derby in Accra.
The 34-year-old has made a return to the Ghana Premier League for the first time since 2003 when he left Liberty Professionals for Udinese.
He is currently Ghana’s all-time top scorer and most capped player, having netted 51 goals in 109 internationals for the Black Stars.
The Legon versus Chelsea clash was originally set to follow a clash between Hearts of Oak and Aduana Stars but the fixture was called off on Friday evening over confirmed cases of coronavirus infections within the camp of the former side.